Unreasonable inventors.
Impossible challenges

It takes an unreasonable belief to achieve the impossible. This is what we invest in and create at Main Sequence

Unreasonable Inventors

Story of industries and challenges with the people that make it happen.

Our Latest Investments

Six Challenges

We love companies that solve one or more of these challenge areas. Explore each one below and get to know some of the companies we have already backed.

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Deep Tech Adventures Newsletter

Deep Tech Adventures is our monthly newsletter sharing the latest in what we are seeing & thinking about plus the latest news from our portfolio.